Principal Investigator

Dr. Hannah Shafaat

Hannah grew up on the South End of Whidbey Island, Washington, which is only connected to the “mainland” by ferry boat. She earned her B.S. in Chemistry from the California Institute of Technology (Caltech) in 2006, where she performed research on spectroscopic endospore viability assays with Adrian Ponce (NASA Jet Propulsion Laboratory) and Harry Gray. She pursued her Ph.D. in Physical Chemistry from the University of California, San Diego (UCSD) in 2011, under the direction of Professor Judy Kim, as an NSF Graduate Research Fellow and a National Defense Science and Engineering Graduate Fellow. During her graduate research, she used many different types of spectroscopy to study the structure and dynamics of amino acid radical intermediates in biological electron transfer reactions. After earning her Ph.D., Hannah moved across the ocean to Germany to study hydrogenase and oxidase enzymes and learn advanced EPR techniques as a Humboldt Foundation Postdoctoral Fellow working under Director Wolfgang Lubitz at the Max Planck Institute for Chemical Energy Conversion. Hannah began her independent career at The Ohio State University in 2013, where she was awarded the NSF CAREER award in 2015 to support work on hydrogenase mimics and the DOE Early Career award in 2017 to support the group’s research on one-carbon activation in model nickel metalloenzymes. The group has also received support for their research on heterobimetallic Mn/Fe cofactors through the NIH R35 MIRA program. Hannah was awarded the 2018 Sloan Research Fellowship and the 2019 Ed Stiefel Young Investigator Award for research on Metals in Biology. Hannah is also an Associate Editor at Chemical Science, the flagship journal of the Royal Society of Chemistry, where she enjoys seeing all the great bioinorganic work that is submitted there (and hopes to see more!). Hannah and her group moved to UCLA in 2023 and are thoroughly enjoying the new adventures and opportunities that California offers!

Email: shafaat [at] ucla [dot] edu

Fun Fact: Hannah is a big fan of stand-up paddleboarding, kayaking, and hiking; she has summited South Sister, the highest of the Three Sisters mountain chain, in central Oregon, and looks forward to tackling more mountains!

View CV

Postdoctoral Scholars

Dr. Yuri Lee

Yuri is from Seoul, South Korea. She graduated from Seoul Women’s University with a B.S. in Chemistry and Bio & Environmental technology as a double major (2012). She then pursued her M.S. in Molecular Biology and Genetics at Seoul National University (2014), where she studied the antimicrobial and hemolytic effects of small peptides under the supervision of Professor Jaehoon Yu. She came to the States to start Ph.D. studies at the University of Kansas, where she was trained as a bioinorganic scientist while working with manganese and late transition metal model complexes for structure-reactivity correlations under the guidance of Professor Timothy Jackson. After earning her Ph.D. in Chemistry (2021), she joined the Shafaat group to explore and establish structure-reactivity relationships of the active site in the heterobimetallic Mn/Fe R2-like ligand-binding oxidase protein (R2lox) using multiple spectroscopic techniques.

Email: yuri [at] chem [dot] ucla [dot] edu

Fun Fact: Yuri likes swimming and plans to learn scuba diving in the near future.

Dr. Kevin E. Rivera Cruz

Kevin earned his B.S. in Chemistry from the University of Puerto Rico (UPR) in 2019, where he performed computational and synthetic inorganic chemistry research in close collaboration with Professor Dalice Piñero (University of Puerto Rico Rio Piedras) and Professor Dalvin Mendez (University of Puerto Rico Cayey) as a National Institute of Health – Research Initiative for Scientific Enhancement (NIH-RISE) and National Science Foundation Louis Stoke Alliances for Minority Participation (NSF-LSAMP) scholar. He then completed his Ph.D. in Inorganic Chemistry from the University of Michigan in 2024, under the mentorship of Professor Charles C.L. McCrory and Paul M. Zimmerman. At the University of Michigan, he was awarded a Department of Energy sponsored GEM Consortium Fellowship, an NSF-Graduate Research Fellowship, and National Academies of Science, Engineering and Medicine-Ford Fellowship. During his graduate research, as a co-mentored student, he specialized in bridging the field of experimental molecular electrocatalysis with first principal calculations during his dissertation work titled “Modulating CO2 Reduction Activity by Systematically Modifying the Catalyst Electronic Structure,” which involved modeling and correlating at an atomistic scale the reaction mechanism for CO2 Reduction Reaction (CO2RR) with bulk scale electrochemical parameters. Under the support of the University of California President’s Postdoctoral Fellowships Program and the National Science Foundation ASCEND Postdoctoral Fellowship, in the Shafaat group, his research goal is harnessing artificial metalloenzymes for selective Carbon-Carbon coupling, aiming to develop a new biocatalytic approach for characterizing the carbon-carbon (C–C) bond-forming reaction on nickel-substituted azurin (NiAz), an Acetyl-CoA Synthase (ACS) model protein. Beyond his academic track record, he has strived to serve as a leader and a mentor and increase the participation of students from underrepresented backgrounds in Puerto Rico and in the continental United States as part of programs such as NSF-LSAMP, NIH-RISE,  the Society for Advancement of Chicanos/Hispanics and Native American in Science (SACNAS), OutinSTEM, and other professional organizations emphasizing the importance of collaboration in scientific research and his commitment to diversity and inclusion in academia. To learn more, please visit Kevin’s personal website.

Email: kriverac [at] chem [dot] ucla [dot] edu

Fun Fact: When he is not in lab, he will most like be visiting a National Park. His personal goal is to do at least 2 national parks per year.

Graduate Students

Josephine Gan

Josephine is from Guangdong, China. She graduated from Brandeis University in 2018 with a B.S. in Chemistry and Biochemistry. While at Brandeis, Josephine worked on turing pattern formation in reaction-diffusion systems with external perturbations. After she graduated, she worked as a research assistant at the Hong Kong University of Science and Technology investigating ATM loss in the autophagy-lysosomal pathway. Josephine joined the Ohio State Chemistry and Biochemistry program in the biological division at OSU in 2019. Her current project focuses on characterization of R2lox heterometallic cofactors using EPR spectroscopy and DFT calculations.

Email: ygan161 [at] ucla [dot] edu

Fun Fact: Josephine did ballet dance for 8 years and still goes dancing in her free time.

Henry Teptarakulkarn

Henry is from Bangkok, Thailand. He attended Mahidol University (MU) where he received a B.Sc. (2020) and a M.Sc. (2021) in Chemistry. While at MU, he conducted research on the effects of redox-inactive metal cations in secondary coordination sphere on redox property and catalytic activity of iron-NNN (pincer) complexes under the supervision of Dr. Teera Chantarojsiri. He is currently pursuing a Ph.D. as a member of the UCLA Chemistry and Biochemistry program with a biophysics specialization. His current projects combine different semi-synthetic approaches, NMR spectroscopy, and other characterization techniques to understand the nature of metal-substituted rubredoxin, a protein-based model for [NiFe]-hydrogenases.

Email: Teptarakulkarn [at] chem [dot] ucla [dot] edu

Fun Fact: In his occasional free time Henry volunteers at the LA Animal Shelter, teaching the dogs and cats cool chem facts.

Nari Tao

Nari grew up in Nanjing, China. She graduated from New York University with a B.S. in Chemistry and a minor in Physics. During her undergraduate studies, she worked on machine learning for organometallics and on optimizing Ni-H catalyzed reactions. After she graduated, she worked on discovering the structure-reactivity relationship of Ni-catalyzed Suzuki coupling using machine learning. Nari is pursuing a Ph.D. as a member of the Shafaat Lab. Her project focuses on the computational design, synthesis, and characterization of butyrylcholinesterase for catalytic organophosphine hydrolase.

Email: rantaoo [at] chem [dot] ucla [dot] edu

Fun Fact: Nari enjoys pop music, swimming, and cooking. She used to practice playing the keyboard with a band.

Aadhishre Kasat

Aadhishre is from Nashik, India. She is in the Molecular Biology Interdepartmental program (MBIDP) specifically in the Biochemistry, Biophysics and Structural Biology home area. She completed her B.S. in Biochemistry and Creative Writing at the University of Wisconsin-Madison in 2022. At Wisconsin, Aadhishre worked in Professor Andrew Buller’s lab where she helped develop and engineer an enzymatic pathway for the biocatalytic synthesis of 1,2-amino alcohols. In the Shafaat lab, Aadhishre is keen to explore the enzymatic activity and mechanism of R2lox, a heterobimetallic Mn/Fe metalloprotein, using bioinformatics and biochemical tools.

Email: akasat [at] chem [dot] ucla [dot] edu

Fun Fact: In her free time, Aadhishre enjoys running by the beach, reading, cooking, and bragging about her triple scorpio identity.

Kathryn Woodburn

Kathryn grew up in Cupertino, CA. She decided to move north and experience living and learning in the Pacific Northwest, graduating with a B.A. in Chemistry from Whitman College in 2023. During her time at Whitman, she investigated the kinetics and co-product evolution of zinc sulfide nanocrystals from single and dual source precursors under the guidance of Professor Mark Hendricks. Inspired by her mentors, Kathryn decided to pursue a Ph.D. in Inorganic Chemistry at UCLA beginning Fall 2023. Pivoting from materials to bioinorganic chemistry, her research focuses on probing enzymatic substrate channel design and binding in nickel-substituted azurin as a model to mimic acetyl coenzymeA synthase reactivity.

Email: kwoodburn [at] chem [dot] ucla [dot] edu

Fun Fact: Kathryn loves to swim, hike, and explore National Parks. Her favorites so far are Yosemite, Grand Teton, and Glacier.

Benjamin Nguyen

Ben hails from Torrance, California, and holds a B.S. in Biochemistry from the University of California, Los Angeles (UCLA). As a transfer student at UCLA, Ben immersed himself in the exploration of novel spectroscopic methods under the guidance of Professor Justin Caram. His passion for the subject prompted him to pursue a Ph.D. in Physical Chemistry through enrollment in UCLA’s chemistry graduate program. Ben’s research focuses on the application of resonance Raman spectroscopy and EPR techniques to unravel the intricacies of interactions within metal-substituted rubredoxin.

Email: bennguyen [at] chem [dot] ucla [dot] edu

Fun Fact: Ben was classically trained on the piano for 15 years, starting at the age of 3.

Itzel Vaca

Itzel is from Mexicali, Mexico. She attended UCSD for her undergraduate studies and first started doing research with the Figueroa group. The scope of her project focused on the synthesis of low-valent metal coordination polymers supported by m-terphenyl isocyanide ligands. After graduating in 2018 with a B.S. in Chemistry, she then ventured off into biotech industry for a couple years and became a part of the Sirigen R&D team. During this time, she worked on the development of fluorescent dyes for flow cytometry. In 2023, Itzel joined the UCLA PhD program with a specialization in Chemical Biology. Her current project in the Shafaat group focuses on building a protein based model for carbon monoxide dehydrogenase to understand its reactivity and mechanism for CO2/CO conversion. 

Email: itzelpvaca [at] chem [dot] ucla [dot] edu

Fun Fact: She is obsessed with boba and it’s super hard to make her mad (unless it’s her sister).

Griffin Eden

Griffin Eden was born in Boston MA, but grew up in the small town of North Bend, WA. He received his undergraduate degree from Occidental College in 2023, graduating with double majors in Chemistry and Spanish, while doing inorganic research in the Hill group. During undergrad, Griffin spent his time researching potential alternative uses of NiFe-hydroxide catalysts, which are usually associated with water splitting reactions. From this experience, as well as from influences gained working in industry at the Promega Corporation, Griffin developed a deep interest for electrochemistry, hydrogen evolving catalysts, and oxygen sensitive synthesis. Starting his pursuit of a doctorate degree at UCLA in 2023, Griffin joined the  Shafaat lab to research analogous NiRd hydrogen evolving catalysts, with the added complexity of a protein backbone and tunable secondary structure.

Email: griffinaeden [at] chem [dot] ucla [dot] edu

Fun Fact: In his free time, Griffin loves to play bass and practice Brazilian Jiu Jitsu. He used to be deeply involved in downhill longboarding, but since moving to LA has decided it is too dangerous.

Postbaccalaureate Scholars

Paul “Minh” Lam

Minh is from Southern California. He graduated with a B.S. from Cal Poly Pomona where he did research on the deoxydehydration reaction of vicinal diols using acac and salan based molybdenum catalysts under Prof. Alex John. His goal was catalytic optimization and mechanistic studies using microwave assisted catalysis to compare to traditional heating conventions. Currently, he is working in the Shafaat group on a synthetic project involving hydrogenases.

Email: pmlamvy [at] g [dot] ucla [dot] edu

Fun Fact: In high school, Minh investigated the effects of different electrolytes on water-splitting electrolysis (2H2O to 2H2 + O2) using a self made apparatus consisting of a plastic food tub and carbon electrodes scavenged from lantern batteries. Little did he know he would once again work with hydrogen chemistry. His latest obsession is the remote controlled rotovap which he is holding in his hand.

Undergraduate Students

Sofia Ando

Sofia is an undergraduate student majoring in chemistry and was born in Bangkok, Thailand before she moved to Walnut Creek, CA. She joined the Shafaat Lab in her second year as part of the Rubredoxin team, investigating the role of Fe in the active site of [NiFe] hydrogenase.

Email: sofiando [at] g [dot] ucla [dot] edu

Fun Fact: Sofia likes to crochet lopsided beanies and scarves, but is looking to learn how to make stuffed animals.

Megan Huang

Megan grew up in Irvine, CA and is an undergraduate majoring in Computational and Systems Biology. She joined the Shafaat Lab in her first year and works on the project focusing on R2lox, a heterobimetallic Mn/Fe protein.

Email: meganghuang [at] g [dot] ucla [dot] edu

Fun Fact: Megan likes drawing botanical illustrations and raising insects (& their respective host plants).

Isaiah Ervin

Isaiah is an undergraduate student born and raised in Fullerton, CA. While pursuing a degree in materials engineering, Isaiah joined the Shafaat Lab during his first year of college with the intention of gaining hands-on research experience. He is part of the azurin task force, working to model and understand acetyl coenzyme-A synthase reactivity through a nickel-substituted azurin protein scaffold.

Email: iervin1811 [at] g [dot] ucla [dot] edu

Fun Fact: When Isaiah was 11 years old, he was an actor in the movie “Too Hip for the Room.”

Ryan Bennett

Hailing from Oak Park, California, Ryan is an undergraduate student pursuing a bachelor’s degree in biochemistry. Ryan became part of the Shafaat Lab during his freshman year of college, eager to learn and explore chemistry beyond the classroom. His current research investigates the reactivity of carbon monoxide dehydrogenase and its mechanism for bidirectionally converting CO and CO2.

Email: rbennett01 [at] g [dot] ucla [dot] edu

Fun Fact: Ryan is on a mission to find the best cold brew coffee in Los Angeles, and has even begun working on his own recipe. 

Lab Alumni

Postdoctoral Fellows

  • Dr. Adam Jenkins, 2023
  • Dr. Chandradeep Ghosh, 2020
    • Postdoctoral researcher in the Bankaitis lab at Texas A&M University
  • Dr. Michael Stevenson, 2017

Graduate Students

  • Dr. Alina Yerbulekova, 2024
  • Dr. Ashlee Wertz, 2024
    • Patent Examiner for the U.S. Patent and Trademark Office
  • Dr. Luke Lewis, 2023
  • Joe Hazel
    • Ph.D. candidate in the OSU chemistry department with advisor Mark Foster
  • Dr. Regina Treviño
  • Dr. Sean Marguet, 2020
    • Research and innovative chemist at Geo. Pfau’s Sons Company, Inc. in Jeffersonville, IN
  • Dr. Effie Kisgeropoulos, 2020
    • Staff scientist at National Renewable Energy Laboratory (NREL) working for Dr. Paul King
  • Dr. Shelby Behnke, 2019
    • Process Engineer at Intel in Portland, OR
  • Dr. Camille Schneider, 2019
    • Employee at CAS in Columbus, Ohio
  • Clayton Wilson, M.S., 2019
  • Dr. Anastasia Manesis, 2018
  • Dr. Jeffrey Slater, 2018
  • Dr. Pearson Maugeri, 2017
    • Yield Engineer at Intel

Undergraduate Students

  • Sofia Lombardo, B.S., 2024
  • Peter Moore, B.S., 2023
  • Riley Stein, B.S., 2023
    • Inorganic chemistry graduate student in the Manesis Lab at UIUC
  • Jonathan McHenry, B.S., 2023
  • Sophia Sterling
  • Sierra Cady, B.S., 2021
  • Ella Troy
  • Kessie Naughton, B.S., 2019
  • Zach Smith, B.A., 2018
  • Jess Fulton
  • Ayla Robinson, B.S., 2018
  • Tim O’Connor, B.S., 2018
  • Alex Leveto, B.S., 2018
  • Nicholas Travelas, B.S., 2017
  • Matthew O’Connor, B.A., 2016
  • Haleigh Monaco, B.S., 2015
  • Sabrina Cirino, B.S., 2015